Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function
Volume: 111, Issue: 8
Published: Feb 10, 2014
Abstract
Significance The mechanistic or mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase that integrates various environmental signals/cues to regulate cell growth, proliferation, metabolism, and survival. The promyelocytic leukemia zinc-finger transcription factor (PLZF) is known to be critical not only for invariant natural killer T ( i NKT)-cell development and effector program differentiation of...
Paper Details
Title
Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function
Published Date
Feb 10, 2014
Volume
111
Issue
8
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