MicroRNA-17-92 cluster regulates osteoblast proliferation and differentiation
Abstract
MicroRNAs (miRNAs) have been identified to play important functions during osteoblast proliferation, differentiation, and apoptosis. The miR-17~92 cluster is highly conserved in all vertebrates. Loss-of-function of the miR-17-92 cluster results in smaller embryos and immediate postnatal death of all animals. Germline hemizygous deletions of MIR17HG are accounted for microcephaly, short stature, and digital abnormalities in a few cases of...
Paper Details
Title
MicroRNA-17-92 cluster regulates osteoblast proliferation and differentiation
Published Date
May 15, 2013
Journal
Volume
45
Issue
2
Pages
302 - 310
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