Characterization and functional assessment of Clostridium histolyticum class I (C1) collagenases and the synergistic degradation of native collagen in enzyme mixtures containing class II (C2) collagenase.

Volume: 43, Issue: 9, Pages: 3171 - 3175
Published: Nov 1, 2011
Abstract
null null Objectives null null Clostridium histolyticum null expresses two classes of collagenases, C1 and C2. However, degradation of these enzymes by proteases during the fermentation or purification process may lead to numerous molecular forms that lead to inconsistent release of islets from human pancreata. This report defines the amino acid sequence of the truncated forms of C1 (C1b or C1c) that contain a single collagen-binding domain...
Paper Details
Title
Characterization and functional assessment of Clostridium histolyticum class I (C1) collagenases and the synergistic degradation of native collagen in enzyme mixtures containing class II (C2) collagenase.
Published Date
Nov 1, 2011
Volume
43
Issue
9
Pages
3171 - 3175
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