New gluconamide-type cationic surfactants: Interactions with DNA and lipid membranes
Abstract
New linear cationic surfactants – 2-(alkyldimethylammonio)ethylgluconamide bromides, denoted as CnGAB, n = 10, 12, 14 and 16 – were synthesized from natural resources and characterized with respect to their potential as gene-delivery agents in gene therapy applications. Interactions with plasmid DNA and with model membranes were studied both experimentally and theoretically. The compounds with n = 12, 14 and 16 show exponentially increasing...
Paper Details
Title
New gluconamide-type cationic surfactants: Interactions with DNA and lipid membranes
Published Date
Oct 1, 2013
Journal
Volume
180-181
Pages
44 - 54
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