Original paper

Structure, function and properties of antibody binding sites

Volume: 217, Issue: 1, Pages: 133 - 151
Published: Jan 1, 1991
Abstract
Do antibody combining sites possess general properties that enable them to bind different antigens with varying affinities and to bind novel antigens? Here, we address this question by examining the physical and chemical characteristics most favourable for residues involved in antigen accommodation and binding. Amphipathic amino acids could readily tolerate the change of environment from hydrophilic to hydrophobic that occurs upon...
Paper Details
Title
Structure, function and properties of antibody binding sites
Published Date
Jan 1, 1991
Volume
217
Issue
1
Pages
133 - 151
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