Tenofovir-based alternate therapies for chronic hepatitis B patients with partial virological response to entecavir

Summary Entecavir ( ETV ) is a first‐line antiviral therapy for treating chronic hepatitis B ( CHB ); however, some patients have suboptimal response to ETV . Currently, there are limited data on how to approach these patients. Therefore, our aim was to compare the effectiveness of two alternate therapies – tenofovir ( TDF ) monotherapy and combination therapy of ETV + TDF – in CHB patients with ETV partial virological response. We conducted a...