The clinical and anatomical heterogeneity of environmental dependency phenomena

Following damage to the frontal lobes, the observation of patients presenting with environmental dependency syndrome (EDS), particularly with its two main components—grasping and imitation behavior, provides a unique opportunity to gain new insights into the neural bases of human autonomy and free-will. In the present study, thirty-nine patients with frontal lobe dysfunction [21 with progressive supranuclear palsy (PSP), and 18 with the...