The Fall of a Dogma? Unexpected High T-Cell Memory Response to Staphylococcus aureus in Humans

Volume: 212, Issue: 5, Pages: 830 - 838
Published: Sep 1, 2015
Abstract
INTRODUCTION Though Staphylococcus aureus is a major pathogen, vaccine trials have failed. In contrast, class-switched antibodies specific to S. aureus are common, implying immune memory formation and suggesting a large pool of S. aureus-reactive helper T-cells. OBJECTIVE To elucidate the cellular arm of S. aureus-specific immune memory, the T-cell response in humans was characterized. METHODS The proliferative response of human peripheral blood...
Paper Details
Title
The Fall of a Dogma? Unexpected High T-Cell Memory Response to Staphylococcus aureus in Humans
Published Date
Sep 1, 2015
Volume
212
Issue
5
Pages
830 - 838
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