Single-channel recordings of two types of calcium channels in rat pancreatic beta-cells
Abstract
Using the cell-attached configuration of the patch clamp technique, we have identified two different types of Ca channels in rat pancreatic beta-cell membranes. The two channels differ in single channel conductance, voltage dependence, and inactivation properties. The single-channel conductance, measured with 100 mM Ba2+ in the pipette, was 21.8 pS for the large channel and 6.4 pS for the small channel. The large-conductance channel is similar...
Paper Details
Title
Single-channel recordings of two types of calcium channels in rat pancreatic beta-cells
Published Date
Aug 1, 1990
Journal
Volume
58
Issue
2
Pages
567 - 571
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