Neuronal migration disorders: clinical, neuroradiologic and genetics aspects
Abstract
Disorders of neuronal migration are a heterogeneous group of disorders of nervous system development. One of the most frequent disorders is lissencephaly, characterized by a paucity of normal gyri and sulci resulting in a ‘smooth brain’. There are two pathologic subtypes: classical and cobblestone. Six different genes could be responsible for this entity (LIS1, DCX, TUBA1A, VLDLR, ARX, RELN ), although co‐delection of YWHAE gene with LIS1 could...
Paper Details
Title
Neuronal migration disorders: clinical, neuroradiologic and genetics aspects
Published Date
Jan 29, 2009
Journal
Volume
98
Issue
3
Pages
421 - 433
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