Transpulmonary hypothermia: A novel method of rapid brain cooling through augmented heat extraction from the lungs

Aim Delay in instituting neuroprotective measures after cardiac arrest increases death and decreases neuronal recovery. Current hypothermia methods are slow, ineffective, unreliable, or highly invasive. We report the feasibility of rapid hypothermia induction in swine through augmented heat extraction from the lungs. Methods Twenty-four domestic crossbred pigs (weight, 50–55 kg) were ventilated with room air. Intraparenchymal brain temperature...