Genotyping with CRISPR-Cas-derived RNA-guided endonucleases

Published on May 1, 2014in Nature Communications11.88
· DOI :10.1038/ncomms4157
Jong Min Kim21
Estimated H-index: 21
Daesik Kim12
Estimated H-index: 12
+ 1 AuthorsJin-Soo Kim52
Estimated H-index: 52
Cas9 RNA-guided engineered nucleases (RGENs) induce site-specific DNA cleavages in cultured cells and organisms and are used widely as genome-editing tools. Here, the authors develop an RGEN-based technology to genotype both RGEN-induced mutations and cancer-associated mutations in human cell lines.
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  • Citations (60)
#1Young Hoon Sung (Yonsei University)H-Index: 10
#2Jong Min Kim (SNU: Seoul National University)H-Index: 1
Last.Cheol-Hee Kim (CNU: Chungnam National University)H-Index: 36
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#1Seung Woo Cho (SNU: Seoul National University)H-Index: 25
#2Sojung Kim (SNU: Seoul National University)H-Index: 10
Last.Jin-Soo Kim (SNU: Seoul National University)H-Index: 52
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#1Seung Woo Cho (SNU: Seoul National University)H-Index: 25
#2Jihyun Lee (SNU: Seoul National University)H-Index: 3
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#1Scott J. Gratz (UW: University of Wisconsin-Madison)H-Index: 9
#2Alexander M. Cummings (UW: University of Wisconsin-Madison)H-Index: 3
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#1Haoyi Wang (MIT: Massachusetts Institute of Technology)H-Index: 24
#2Hui Yang (MIT: Massachusetts Institute of Technology)H-Index: 16
Last.Rudolf Jaenisch (MIT: Massachusetts Institute of Technology)H-Index: 173
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Cited By60
#1Alex K. Datsomor (NTNU: Norwegian University of Science and Technology)
#2Nikola Zic (NTNU: Norwegian University of Science and Technology)
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#1Ivana Indikova (University of Veterinary Medicine Vienna)H-Index: 3
#2Stanislav Indik (University of Veterinary Medicine Vienna)H-Index: 10
#1Renyu Li (UVA: University of Virginia)
#2Charles Vavrik (UVA: University of Virginia)
Last.Cristian H. Danna (UVA: University of Virginia)
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#1Sukumar Biswas (SJTU: Shanghai Jiao Tong University)H-Index: 1
#2Rong Li (SJTU: Shanghai Jiao Tong University)H-Index: 4
Last.Jianxin Shi (SJTU: Shanghai Jiao Tong University)H-Index: 19
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#1Arivazhagan Rajendran (Kyoto University)H-Index: 19
#2Narumi Shigi (UTokyo: University of Tokyo)H-Index: 7
Last.Makoto Komiyama (Ocean University of China)H-Index: 49
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View next paperMultiplex Genome Engineering Using CRISPR/Cas Systems