Control of colorectal cancer using organotin polymers
Published on Oct 2, 2014in Journal of the Chinese Advanced Materials Society
· DOI :10.1080/22243682.2014.966274
The efforts described in this paper are aimed at designing organotin polymers that control the growth of various cancers; here colorectal cancer and to identify structure/property relationships that will assist in this goal. The growth of colorectal cancer is affected employing a wide range of organotin condensation polymers. The EC50 values are primarily dependent on the nature of the Lewis base but the CI50 value is dependent on both the nature of the Lewis base and Lewis acid. EC50 values down to the nanograms/mL range are found. A number of products exhibit CI50 values greater than 2.