Mechanism of chromosomal DNA replication initiation and replication fork stabilization in eukaryotes

Volume: 57, Issue: 5, Pages: 482 - 487
Published: Apr 4, 2014
Abstract
Chromosomal DNA replication is one of the central biological events occurring inside cells. Due to its large size, the replication of genomic DNA in eukaryotes initiates at hundreds to tens of thousands of sites called DNA origins so that the replication could be completed in a limited time. Further, eukaryotic DNA replication is sophisticatedly regulated, and this regulation guarantees that each origin fires once per S phase and each segment of...
Paper Details
Title
Mechanism of chromosomal DNA replication initiation and replication fork stabilization in eukaryotes
Published Date
Apr 4, 2014
Volume
57
Issue
5
Pages
482 - 487
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