Involvement of GABAA-benzodiazepine receptor in the anxiolytic effect induced by hexanic fraction of Rubus brasiliensis

Volume: 61, Issue: 2, Pages: 119 - 126
Published: Jun 1, 1998
Abstract
To investigate the ability of hexanic ethanolic fraction of Rubus brasiliensis Martius (Roseceae), to induce anxiolytic effect and also the possible involvement of the GABA(A)-benzodiazepine receptor complex, male Wistar rats and Swiss mice behaviour were tested in the elevated plus maze (EPM). All the doses of the extract, 50, 100 and 150 mg/kg, administered per gavage (vo), 30 min before the behavioural evaluation, induced an anxiolytic effect...
Paper Details
Title
Involvement of GABAA-benzodiazepine receptor in the anxiolytic effect induced by hexanic fraction of Rubus brasiliensis
Published Date
Jun 1, 1998
Volume
61
Issue
2
Pages
119 - 126
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