Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine.

Volume: 186, Issue: 1, Pages: 67 - 77
Published: Apr 15, 2003
Abstract
Plant phenolics modify the metabolic activation of several carcinogens, including aromatic amines. In this study, we have evaluated the effects of three structurally diversified plant phenolics, protocatechuic acid (PCA), tannic acid (TA) and ellagic acid (EA) on cytochrome p450-dependent enzymes and glutathione S-transferase (GST) activities after oral administration alone or in combination with o-toluidine in rat liver and kidney....
Paper Details
Title
Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine.
Published Date
Apr 15, 2003
Journal
Volume
186
Issue
1
Pages
67 - 77
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