Review paper
Role of the Blood–Brain Barrier in Multiple Sclerosis
Abstract
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system associated with demyelination and axonal loss eventually leading to neurodegeneration. MS exhibits many of the hallmarks of an inflammatory autoimmune disorder including breakdown of the blood-brain barrier (BBB). The BBB is a complex organization of cerebral endothelial cells, pericytes and their basal lamina, which are surrounded and supported by astrocytes and...
Paper Details
Title
Role of the Blood–Brain Barrier in Multiple Sclerosis
Published Date
Nov 1, 2014
Journal
Volume
45
Issue
8
Pages
687 - 697
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