An Extensive Genetic Program Occurring during Postnatal Growth in Multiple Tissues
Abstract
Mammalian somatic growth is rapid in early postnatal life but then slows and eventually ceases in multiple tissues. We hypothesized that there exists a postnatal gene expression program that is common to multiple tissues and is responsible for this coordinate growth deceleration. Consistent with this hypothesis, microarray analysis identified more than 1600 genes that were regulated with age (1 vs. 4 wk) coordinately in kidney, lung, and heart...
Paper Details
Title
An Extensive Genetic Program Occurring during Postnatal Growth in Multiple Tissues
Published Date
Nov 26, 2008
Journal
Volume
150
Issue
4
Pages
1791 - 1800
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