Biomimetic Membrane System Composed of a Composite Interpenetrating Hydrogel Film and a Lipid Bilayer

Published on Oct 23, 2012in Advanced Functional Materials15.621
路 DOI :10.1002/adfm.201200751
Barry Stidder2
Estimated H-index: 2
(UJF: Joseph Fourier University),
Jean-Pierre Alcaraz6
Estimated H-index: 6
(UJF: Joseph Fourier University)
+ 5 AuthorsDonald Martin1
Estimated H-index: 1
(UJF: Joseph Fourier University)
A simple way to form an interpenetrating hydrogel (IPH) by combining a layer-by-layer polyelectrolyte membrane with agarose is reported. The formed IPH membrane is more robust and easily manipulated compared to a polyelectrolyte membrane with the same number of layers. The IPH has good diffusion characteristics and retains the advantageous surface charge from the polyectrolyte composition that facilitates the adsorption of a stable lipid bilayer. The stable adsorption of a lipid bilayer on the IPH creates a biomimetic membrane system that is optimized for utilization in a diffusion chamber.
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  • Citations (5)
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