Published on Apr 24, 2009in Acta Medica Scandinavica
· DOI :10.1111/j.0954-6820.1966.tb04745.x
Mattti J. Karvonen1
Estimated H-index: 1
Gunnar Blomqvist14
Estimated H-index: 14
+ 5 AuthorsAncel Keys71
Estimated H-index: 71
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  • Citations (38)
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Cited By38
#1Hanna Tolonen (National Institute for Health and Welfare)H-Index: 26
#2Annamari Lundqvist (National Institute for Health and Welfare)H-Index: 17
Last. Päivikki Koponen (National Institute for Health and Welfare)H-Index: 17
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2 CitationsSource
#1Jaakko Reinikainen (University of Jyväskylä)H-Index: 2
#2Juha Karvanen (University of Jyväskylä)H-Index: 19
Last. Hanna Tolonen (National Institute for Health and Welfare)H-Index: 26
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Repeated covariate measurements bring important information on the time-varying risk factors in long epidemiological follow-up studies. However, due to budget limitations, it may be possible to carry out the repeated measurements only for a subset of the cohort. We study cost-efficient alternatives for the simple random sampling in the selection of the individuals to be remeasured. The proposed selection criteria are based on forms of the D-optimality. The selection methods are compared with the...
2 CitationsSource
#1Jaakko Reinikainen (University of Jyväskylä)H-Index: 2
#2Juha Karvanen (University of Jyväskylä)H-Index: 19
Last. Hanna Tolonen (National Institute for Health and Welfare)H-Index: 26
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Abstract Objective In epidemiologic follow-up studies, many key covariates, such as smoking, use of medication, blood pressure, and cholesterol, are time varying. Because of practical and financial limitations, time-varying covariates cannot be measured continuously, but only at certain prespecified time points. We study how the number of these longitudinal measurements can be chosen cost-efficiently by evaluating the usefulness of the measurements for risk prediction. Study Design and Setting T...
2 CitationsSource
#1Jaakko Reinikainen (National Institute for Health and Welfare)H-Index: 2
#2Tiina Laatikainen (National Institute for Health and Welfare)H-Index: 53
Last. Hanna Tolonen (National Institute for Health and Welfare)H-Index: 26
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Background Systolic blood pressure, total cholesterol and smoking are known predictors of cardiovascular disease (CVD) mortality. Less is known about the effect of lifetime accumulation and changes of risk factors over time as predictors of CVD mortality, especially in very long follow-up studies. Methods Data from the Finnish cohorts of the Seven Countries Study were used. The baseline examination was in 1959 and seven re-examinations were carried out at approximately 5-year intervals. Cohorts ...
15 CitationsSource
Epidemiological studies can often be designed in several ways, some of which may be more optimal than others. Possible designs may differ in the required resources or the ability to provide reliable answers to the questions under study. In addition, once the data are collected, the selected modeling approach may affect how efficiently the data are utilized. The purpose of this dissertation is to investigate efficient designs and analysis methods in follow-up studies with longitudinal measurement...
#2Ur MathematikH-Index: 1
#3Und StatistikH-Index: 1
#1M. J. Karvonen (Health Science University)H-Index: 1
#2Sven Punsar (Health Science University)H-Index: 31
Altogether 1178 men aged 55–74 were studied at 15-year re-examination of two rural cohorts of initially 1711 men from east and west Finland. At the start, 15 years ago, the mean BPs were 148/89 and 140/82 mmHg in the eastern and western populations, respectively. The difference had now disappeared and changed direction for systolic BP (east 147/85, west 155/84 mmHg). Of those with an initial systolic BP of 170 mmHg or higher, 68/118 (58%) in the east and 33/67 (49%) in the west had died in 15 ye...
25 CitationsSource
#1P. PietinenH-Index: 9
#2Ulla UusitaloH-Index: 25
Last. Jaakko TuomilehtoH-Index: 185
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. A dietary survey concerning 1348 persons aged 25–64 was carried out in connection with the first FINMONICA risk factor survey in the three monitoring areas, North Karelia and Kuopio in the east, and Turku—Loimaa in the south-west in 1982. Three-day food records were used in the dietary assessment. The fat content of the diet in men was 38–39 % of energy in all areas, whereas in women it was about 36 % in the east compared to 38 % in the south-west. The ratio of polyunsaturated to saturated fat...
26 CitationsSource
#1Arpo Aromaa (Social Insurance Institution)H-Index: 75
#2F. Björkstén (Social Insurance Institution)H-Index: 3
Last. M. Tamminen (Social Insurance Institution)H-Index: 2
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. Only small differences in serum cholesterol means and somewhat larger, but still modest differences in log(TG) means were observed, when seven Finnish population groups were compared. Semiurban and industrial groups had the highest triglyceride levels. Cholesterol levels tended to be lower in South Finland than in East or North Finland and lowest in semiurban population groups. Between 15–59 years of age, rural Finns of both sexes had higher and after this age lower cholesterol means than the ...
23 CitationsSource
#1Olli Suhonen (Social Insurance Institution)H-Index: 7
#2Antti Reunanen (Social Insurance Institution)H-Index: 28
Last. K. Pyörälä (Social Insurance Institution)H-Index: 10
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. Suhonen O, Reunanen A, Aromaa A, Knekt P, PyOrAlA K. (Research Institute for Social Security, Social Insurance Institution, Helsinki, Finland.) Four-year incidence of myocardial infarction and sudden coronary death in twelve Finnish population cohorts. The incidence of myocardial infarction (MI) and sudden coronary death in four years was studied in 6510 men and 5800 women, aged 30–59 years, derived from 12 Finnish population cohorts constituting the invited population to a prospective study. ...
10 CitationsSource