Discovering Endophenotypes for Major Depression
Abstract
The limited success of genetic studies of major depression has raised questions concerning the definition of genetically relevant phenotypes. This paper presents strategies to improve the phenotypic definition of major depression by proposing endophenotypes at two levels: First, dissecting the depressive phenotype into key components results in narrow definitions of putative psychopathological endophenotypes: mood bias toward negative emotions,...
Paper Details
Title
Discovering Endophenotypes for Major Depression
Published Date
Jun 23, 2004
Journal
Volume
29
Issue
10
Pages
1765 - 1781
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