Nitrogen Sources Affect Streptolydigin Production and Related Secondary Metabolites Distribution of Streptomyces lydicus AS 4.2501

The effects of nitrogen sources on streptolydigin production and distribution of secondary metabolites were investigated for flask cultured S. lydicus AS 4.2501. When peptone, asparamide, and glutamic acid were examined as the nitrogen source, respectively, liquid chromatography-mass spectrometry (LC-MS) and photodiode array (PDA) analyses revealed the formation of two analogues of streptolydigin in the fermentation broth. When soybean meal was...