Circulating Fibroblast Growth Factors as Metabolic Regulators—A Critical Appraisal
Abstract
The circulating FGFs are a new group of proteins believed to function as classic hormones. With emphasis on human metabolism, we critically review current data, and propose that—although a number of questions remain—circulating FGF23 is pivotal in the control of phosphate and vitamin D metabolism, and may have additional systemic effects, particularly in chronic kidney disease; that FGF19 signaling is important for the regulation of bile acid...
Paper Details
Title
Circulating Fibroblast Growth Factors as Metabolic Regulators—A Critical Appraisal
Published Date
Dec 1, 2012
Journal
Volume
16
Issue
6
Pages
693 - 705
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