Behavioral Pharmacology of Zolpidem Relative to Benzodiazepines A Review

Zolpidem, an imidazopyridine that purportedly binds selectively to certain GABAA receptor subtypes, is the most commonly prescribed hypnotic. The present article critically reviewed the extant experimental literature to determine whether the behavioral pharmacologic profile of zolpidem also differs from that of benzodiazepines. Specific topics that are reviewed include: 1) reinforcing effects and abuse potential, 2) discriminative-stimulus...