Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Abstract
Adiponectin (also known as 30-kDa adipocyte complement-related protein; Acrp30) is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Levels of adiponectin in the blood are decreased under conditions of obesity, insulin resistance and type 2 diabetes. Administration of adiponectin causes glucose-lowering effects and ameliorates insulin resistance in mice. Conversely, adiponectin-deficient mice exhibit...
Paper Details
Title
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Published Date
Jun 12, 2003
Journal
Volume
423
Issue
6941
Pages
762 - 769
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