Review paper
-induced macrophage death: the role of caspase-1 in death and inflammation
Abstract
Salmonella typhimurium invades host macrophages and can induce either an almost immediate cell death or establish an intracellular niche within the phagocytic vacuole. Rapid cell death depends on the Salmonella pathogenicity island SPI1 and the host protein caspase-1, a member of the pro-apoptotic caspase family of proteases. Caspase-1-dependent cell death leads to the activation of the potent pro-inflammatory cytokines interleukin (IL)-1beta...
Paper Details
Title
-induced macrophage death: the role of caspase-1 in death and inflammation
Published Date
Nov 1, 2001
Journal
Volume
3
Issue
14-15
Pages
1201 - 1212
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Notes
History