Diabetes causes the activation of the pro-ageing miRNA-34a in the human heart
Abstract
Background: Diabetes accelerates cellular ageing, contributing to disease development including cardiovascular diseases (CVD). MicroRNAs (miRs) are short, non-coding RNAs which modulate protein expression by negatively controlling RNA transcription, and are gaining interest due to their pathological role in CVD development. Recent studies showed activation of miR-34a in the ageing heart, contributing to age-related cardiac dysfunction. As...
Paper Details
Title
Diabetes causes the activation of the pro-ageing miRNA-34a in the human heart
Published Date
Jan 1, 2014
Journal
Volume
23
Pages
e24 - e24
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Notes
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