Receptor for protons: First observations on Acid Sensing Ion Channels
Abstract
The history of ASICs began in 1980 with unexpected observation. The concept of highly selective Na(+) current gated by specific receptors for protons was not easily accepted. It took 16 years to get these receptor/channels cloned and start a new stage in their investigation. "The receptor for protons" became ASIC comprising under this name a family of receptor/channels ubiquitous for mammalian nervous system, both peripheral and central. The...
Paper Details
Title
Receptor for protons: First observations on Acid Sensing Ion Channels
Published Date
Jul 1, 2015
Journal
Volume
94
Pages
4 - 8
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Notes
History