Lactobacillus reuteri ingestion and IK_Ca channel blockade have similar effects on rat colon motility and myenteric neurones

We have previously shown that ingestion of Lactobacillus reuteri may modulate colonic enteric neuron activity but with unknown effects on colon motility. The aim of the present report was to elucidate the neuronal mechanisms of action of the probiotic by comparing the effects on motility of L. reuteri ingestion with blockade of a specific ionic current in enteric neurons.We have used intraluminal pressure recordings from ex vivo rat colon...