Improvement of clavulanic acid production by Streptomyces clavuligerus with peanut derivatives

Clavulanic acid (CA) production by Streptomyces clavuligerus was compared in fermentation media containing various nitrogen sources, including soybean meal, peptone, corn steep powder, cotton seed meal, ammonium sulfate, and ammonium nitrate, respectively. The basal fermentation medium was also supplemented with various concentrations of peanut derivatives. The highest CA concentration was obtained in medium containing soybean meal supplemented...