Match!

Abdominal obesity and metabolic syndrome

Published on Dec 1, 2006in Nature43.07
· DOI :10.1038/nature05488
Jean-Pierre Després110
Estimated H-index: 110
(Laval University),
Isabelle Lemieux45
Estimated H-index: 45
Cite
Abstract
Metabolic syndrome is associated with abdominal obesity, blood lipid disorders, inflammation, insulin resistance or full-blown diabetes, and increased risk of developing cardiovascular disease. Proposed criteria for identifying patients with metabolic syndrome have contributed greatly to preventive medicine, but the value of metabolic syndrome as a scientific concept remains controversial. The presence of metabolic syndrome alone cannot predict global cardiovascular disease risk. But abdominal obesity — the most prevalent manifestation of metabolic syndrome — is a marker of 'dysfunctional adipose tissue', and is of central importance in clinical diagnosis. Better risk assessment algorithms are needed to quantify diabetes and cardiovascular disease risk on a global scale.
  • References (92)
  • Citations (2655)
Cite
References92
Newest
#1Andrea Galassi (Tulane University)H-Index: 1
#2Kristi Reynolds (Tulane University)H-Index: 43
Last.Jiang He (Tulane University)H-Index: 99
view all 3 authors...
#1Takashi Kadowaki (Shiga University of Medical Science)H-Index: 121
#2Akira Sekikawa (University of Pittsburgh)H-Index: 26
Last.Y. Kita (Shiga University of Medical Science)H-Index: 10
view all 10 authors...
#1Sotirios Tsimikas (UCSD: University of California, San Diego)H-Index: 68
#2James T. Willerson (St Lukes Episcopal Hospital)H-Index: 68
Last.Paul M. Ridker (Brigham and Women's Hospital)H-Index: 192
view all 3 authors...
Cited By2655
Newest
#1Sandhya Sriram (Agency for Science, Technology and Research)H-Index: 3
#2Chengxiang Yuan (Agency for Science, Technology and Research)H-Index: 1
Last.Shigeki Sugii (Agency for Science, Technology and Research)H-Index: 18
view all 9 authors...
#1Paule V. Joseph (NIH: National Institutes of Health)H-Index: 4
#2Rosario B. Jaime-Lara (NIH: National Institutes of Health)
Last.Wendy A. Henderson (NIH: National Institutes of Health)H-Index: 11
view all 5 authors...
#1Yuan-Yuei Chen (NDMC: National Defense Medical Center)H-Index: 3
#2Tung-Wei KaoH-Index: 9
Last.Wei-Liang Chen (NDMC: National Defense Medical Center)H-Index: 9
view all 9 authors...
#1Keiichi Koizumi (University of Toyama)H-Index: 27
#2Makito Oku (University of Toyama)H-Index: 3
Last.Makoto Kadowaki (University of Toyama)H-Index: 19
view all 10 authors...
View next paperMechanisms linking obesity with cardiovascular disease