Increase in brain stem cytokine mRNA levels as an early response to chemical-induced myelin edema

Volume: 88, Issue: 1-2, Pages: 154 - 164
Published: Aug 1, 1998
Abstract
This study examined the early response of pro-inflammatory and regulatory cytokines in the mouse brain following triethyltin (TET)-induced myelin injury characterized by edematous vacuolation. Following an acute intraperitoneal injection of triethyltin (TET) sulfate (3 mg/kg) to 17-day old CD1 mice, significant increases in brain stem TNF-α and IL-1α mRNA levels occurred at 6 and 24 h, respectively with elevations in TGF-β1 and MIP-1α at 1 h. In...
Paper Details
Title
Increase in brain stem cytokine mRNA levels as an early response to chemical-induced myelin edema
Published Date
Aug 1, 1998
Volume
88
Issue
1-2
Pages
154 - 164
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