Novel objects in a holeboard probe the role of the locus coerulus in curiosity: Support for two modes of attention in the rat.
Abstract
Idazoxan, an alpha 2 adrenoceptor antagonist (2 mg/kg), enhanced novel object investigation in a holeboard in rats as previously reported (V. Devauges & S. J. Sara, 1990). Two weeks of 10 min/day in 37 degrees C water increased dopamine-beta-hydroxylase staining density in the locus coeruleus but did not enhance novel object investigation. In contrast to idazoxan, however, the warm water treatment increased rearing, center entries, and activity,...
Paper Details
Title
Novel objects in a holeboard probe the role of the locus coerulus in curiosity: Support for two modes of attention in the rat.
Published Date
Jan 1, 2003
Journal
Volume
117
Issue
3
Pages
621 - 631
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Notes
History