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Antihypertensive effects exerted by enalapril in mild to moderate hypertension are not associated with changes in the circulating levels of nitric oxide-related markers

Published on Apr 1, 2011in European Journal of Clinical Pharmacology2.77
· DOI :10.1007/s00228-011-1003-x
Pamela S. Silva8
Estimated H-index: 8
(State University of Campinas),
Vanessa Fontana14
Estimated H-index: 14
(USP: University of São Paulo)
+ 3 AuthorsJosé Eduardo Tanus-Santos27
Estimated H-index: 27
(USP: University of São Paulo)
Abstract
Purpose The antihypertensive effects of angiotensin-converting enzyme inhibitors (ACEi) are explained, at least in part, by enhanced bradykinin-dependent nitric oxide (NO) formation and decreased angiotensin II-induced oxidative stress and vasoconstriction. We examined for the first time whether treatment with enalapril increases the plasma levels of markers of NO formation and decreases oxidative stress in mild to moderate hypertensive patients.
  • References (41)
  • Citations (16)
References41
Newest
#1Riccardo Lacchini (State University of Campinas)H-Index: 16
#2Pamela S. Silva (State University of Campinas)H-Index: 8
Last.Jose E. Tanus-Santos (USP: University of São Paulo)H-Index: 25
view all 3 authors...
#1Marcelo F. Montenegro (USP: University of São Paulo)H-Index: 21
#2Lisandra R. Pessa (USP: University of São Paulo)H-Index: 2
Last.Jose E. Tanus-Santos (USP: University of São Paulo)H-Index: 34
view all 6 authors...
#1Sabrina Nagassaki (USP: University of São Paulo)H-Index: 6
#2Rondinelli Donizetti Herculano (USP: University of São Paulo)H-Index: 12
Last.Jose E. Tanus-Santos (USP: University of São Paulo)H-Index: 25
view all 4 authors...
#1Stefany B.A. Cau (USP: University of São Paulo)H-Index: 11
#2Carlos A. Dias-Junior (USP: University of São Paulo)H-Index: 15
Last.Jose E. Tanus-Santos (USP: University of São Paulo)H-Index: 34
view all 6 authors...
Cited By16
Newest
#1Gustavo H. Oliveira-Paula (USP: University of São Paulo)H-Index: 9
#2Riccardo Lacchini (State University of Campinas)H-Index: 16
Last.Jose E. Tanus-Santos (USP: University of São Paulo)H-Index: 25
view all 7 authors...
#1Gustavo H. Oliveira-Paula (USP: University of São Paulo)H-Index: 9
#2Riccardo Lacchini (USP: University of São Paulo)H-Index: 16
Last.Jose E. Tanus-Santos (USP: University of São Paulo)H-Index: 34
view all 3 authors...
#1Jefferson H. Amaral (USP: University of São Paulo)H-Index: 13
#2Graziele C. Ferreira (USP: University of São Paulo)H-Index: 8
Last.José Eduardo Tanus-Santos (USP: University of São Paulo)H-Index: 27
view all 5 authors...
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