Differential regulation of IL-6 and TNF-α via calcineurin in human skeletal muscle cells

Volume: 36, Issue: 3, Pages: 141 - 147
Published: Nov 1, 2006
Abstract
null null Interleukin-6 increases in skeletal muscle during exercise, and evidence points to Ca2+ as an initiator of IL-6 production. However, the signalling pathway whereby this occurs is unknown. One candidate for Ca2+ -mediated IL-6 induction is calcineurin, an activator of NF-AT. Here we investigated whether skeletal myocytes produce IL-6 in a Ca2+/calcineurin-dependent manner, and whether TNF-α, an inducer of IL-6, is affected by these...
Paper Details
Title
Differential regulation of IL-6 and TNF-α via calcineurin in human skeletal muscle cells
Published Date
Nov 1, 2006
Journal
Volume
36
Issue
3
Pages
141 - 147
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.