Branding/Logomark minus Citation Combined Shape Icon/Bookmark-empty Icon/Copy Icon/Collection Icon/Close Copy 7 no author result Created with Sketch. Icon/Back Created with Sketch. Match!

Experimental diuretic effects of Rosmarinus officinalis and Centaurium erythraea

Published on Aug 1, 2000in Journal of Ethnopharmacology 3.41
· DOI :10.1016/S0378-8741(00)00184-7
Mounsif Haloui3
Estimated H-index: 3
(SIDI),
Liliane Louedec28
Estimated H-index: 28
(French Institute of Health and Medical Research)
+ 1 AuthorsBadiaa Lyoussi23
Estimated H-index: 23
(SIDI)
Cite
Abstract
Herbal remedies are widely used in Moroccan pharmacopoeia. We assessed the diuretic effect of two medicinal plants: Rosmarinus officinalis L., Labiatae, and Centaurium erythraea L., Gentianaceae, both reputed for the treatment of urinary ailments. To determine the action of these herbs on urinary volume (UV) and the excretion of sodium (UNaV), potassium (UKV), and chloride (UClV), the aqueous extracts of both plants were administered daily to Wistar rats for 1 week. The concentration of electrolytes and urea in plasma and creatinine clearance were also investigated. Daily oral administration of the aqueous extracts of R. officinalis and C. erythraea at the dose of 10 ml/kg of 8 or 16% extract in distilled water significantly enhanced diuresis in rats compared to the control group from the fifth day of treatment. For R. officinalis at the dose of 8% the peak of urinary excretion of sodium, potassium and chloride was reached after 6 days of treatment (P<0.001). The aqueous extract of of R. officinalis at the dose of 16% did not significantly affect the excretion of water and electrolytes over a similar period but slight increases in urinary excretion of sodium and chloride on the seventh day and of potassium on the sixth day (P<0.05) were observed. No increase was recorded for 24 h urinary excretion of Na+, K+ and Cl− during the first 4 days of treatment for the groups treated with C. erythraea at the doses of 8 and 16% whereas their effects on the same parameters were highly significant thereafter. No change was observed in plasma electrolytes and urea in any group, except for a decrease in sodium and chloride concentration in the group treated with 16% of R. officinalis. A decrease in creatinine clearance was demonstrated after treatment with 8% of R. officinalis and C. erythraea . Our findings demonstrate a diuretic effect of aqueous extracts of R. officinalis L. and C. erythraea L. with the most effective dose for water and electrolyte excretion being 8% for both plants.
  • References (17)
  • Citations (117)
Cite
References17
Newest
Published on Sep 1, 1997in Journal of Ethnopharmacology 3.41
Abderrahim Ziyyat21
Estimated H-index: 21
,
Abdelkhaleq Legssyer18
Estimated H-index: 18
+ 3 AuthorsW Benjelloun1
Estimated H-index: 1
(Al Akhawayn University)
Abstract In order to select the main medicinal plants used in folk medicine to treat arterial hypertension and/or diabetes, a survey was undertaken in different areas of oriental Morocco. The patients (370 women and 256 men) were divided into three groups: diabetics (61%), hypertensives (23%) and hypertensive diabetic persons (16%). On average, 67.5% of patients regularly use medicinal plants. This proportion is perceptibly the same in all groups and does not depend on sex, age and socio-cultura...
Published on Aug 1, 1995in Planta Medica 2.75
Hiroyuki Haraguchi27
Estimated H-index: 27
,
Takashi Saito4
Estimated H-index: 4
+ 1 Authorsアキラ ヤギ27
Estimated H-index: 27
Four diterpenoids, carnosic acid (1), carnosol (2), rosmanol (3), and epirosmanol (4), were isolated as antioxidative agents from the leaves of Rosmarinus officinalis by bioassay-directed fractionation. These diterpenoids inhibited superoxide anion production in the xanthine/xanthine oxidase system. Mitochondrial and microsomal lipid peroxidation induced by NADH or NADPH oxidation were also completely inhibited by these diterpenes at the concentration of 3-30 μM. Furthermore, carnosic acid prote...
Published on Jul 1, 1994in Journal of Ethnopharmacology 3.41
A.A. Al-Hader2
Estimated H-index: 2
(JUST: Jordan University of Science and Technology),
Z.A. Hasan2
Estimated H-index: 2
(JUST: Jordan University of Science and Technology),
M. Aqel11
Estimated H-index: 11
(UJ: University of Jordan)
Abstract The effects of the volatile oil extracted from the leaves of Rosmarinus officinalis on glucose and insulin levels were investigated in normal rabbits, after the administration of an intraperitoneal glucose tolerance test (GTT). Also, the effects of the volatile oil on fasting plasma glucose levels, were studied in alloxan diabetic rabbits. In normal rabbits, the intramuscular (i.m.) administration of the volatile oil (25 mg/kg) produced 20% ( P P P P R. officinalis volatile oil increase...
Published on Aug 1, 1993in Journal of Ethnopharmacology 3.41
L. Panizzi10
Estimated H-index: 10
,
Guido Flamini37
Estimated H-index: 37
(UniPi: University of Pisa)
+ 1 AuthorsIvano Morelli38
Estimated H-index: 38
(UniPi: University of Pisa)
Abstract Essential oils from Satureja montana L., Rosmarinus officinalis L., Thymus vulgaris L., and Calamintha nepeta (L.) Savi, were chemically analysed and their antimicrobial and fungicide activities evaluated on the basis of their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). All four oils have a biotoxic effect, the most active being those from Calamintha and Thymus .
Published on Dec 1, 1991in Journal of Ethnopharmacology 3.41
Jamal Bellakhdar1
Estimated H-index: 1
,
Renée Claisse1
Estimated H-index: 1
+ 1 AuthorsChafique Younos19
Estimated H-index: 19
(Metz)
Abstract The traditional uses of plants for medicine were studied in Morocco. To this date, 231 medicinal plants belonging commonly to the Moroccan pharmacopoea have been identified and are presented in a table with the vernacular name in Arabic and/or Berber, the ecological distribution, the useful part and the medicinal use. The study of the main therapeutic indications of the medicinal plants gives a clear picture of the health problems which are treated by traditional medicine in Morocco.
Published on May 1, 1991in Journal of Ethnopharmacology 3.41
M. Aqel11
Estimated H-index: 11
(UJ: University of Jordan)
Abstract The effects of the volatile oil of Rosmarinus officinalis leaves on the tracheal smooth muscle of rabbit and guinea pig were tested in vitro using isolated tracheal strips. The volatile oil of R. officinalis leaves inhibited the contractions of rabbit tracheal smooth muscle induced by acetylcholine stimulation and the contractions of guinea pig tracheal smooth muscle induced by histamine stimulation. Also, the volatile oil inhibited the contractions of rabbit and guinea pig tracheal smo...
Published on Feb 1, 1991in Planta Medica 2.75
Tayfun Berkan3
Estimated H-index: 3
,
Levent Üstünes8
Estimated H-index: 8
+ 1 AuthorsAsli Özer6
Estimated H-index: 6
Erytraea centaurium is a plant which is used in the treatment of various inflammatory conditions in popular medicine. The extract exhibited antiinflammatory and antipyretic activity although no analgesic activity was observed.
Published on Jan 1, 1991in Pharmaceutica Acta Helvetiae
J. L. Lamaison7
Estimated H-index: 7
,
C. Petitjean-Freytet7
Estimated H-index: 7
,
A. Carnat7
Estimated H-index: 7
Hydroalcholic extracts from four native medicinal Lamiaceae, Lycopus europaeus L., Melissa officinalis L., Origanum vulgare L. and Prunella vulgaris L. have shown significant antioxidative activities, by free radical scavenger effect on DPPH, compared with those of Rosmarinus officinalis L. and Salvia officinalis L. extracts. The antioxidative activity was partly in relation to the rosmarinic acid content. The major hydroxycinnamic compound, quantitatively determinated by HPLC, was present in la...
Cited By117
Newest
Elif Bozdogan Sert , Musa Türkmen (Mustafa Kemal University), Mehmet Cetin11
Estimated H-index: 11
(Kastamonu University)
Pollution has become a problem on a global scale and poses a significant risk in terms of human health and natural ecosystems. Generally, the biggest sources of pollution are municipal and industrial facilities. However, traffic-related air pollution cannot be overlooked as a dangerous source either. There have been various methods of interventions to measure and reduce the risk and effects of traffic-related pollution. In the case of measuring, the use of certain plant species that can accumula...
Published on Jun 1, 2019in Journal of Ethnopharmacology 3.41
Nawel Hamza1
Estimated H-index: 1
(University of Bordeaux),
Bénédicte Berké11
Estimated H-index: 11
(University of Bordeaux)
+ 3 AuthorsNicholas Moore49
Estimated H-index: 49
(University of Bordeaux)
Abstract Ethnopharmacological relevance Plants are traditionally used in Algeria to treat many disorders, including diabetes mellitus. Knowledge of the plants that are used may provide insight on their properties, for further exploration. This study reviewed all the available published and unpublished reports concerning the use of herbal medicines in the treatment of diabetes in Algeria. Aim of the study To describe the plants used in Algeria to treat diabetes, as reported in the literature. Mat...
Published on Jun 1, 2019in Industrial Crops and Products 4.19
Abdelhakim Bouyahya10
Estimated H-index: 10
(Mohammed V University),
Omar Belmehdi2
Estimated H-index: 2
(Abdelmalek Essaâdi University)
+ 6 AuthorsYoussef Bakri13
Estimated H-index: 13
(Mohammed V University)
Abstract This work is aimed the study of volatile compounds of Centauruim erythraea Raphin at three developmental stages (vegetative, flowering and post-flowering) and the investigation of their in vitro antioxidant, antidiabetic, dermatoprotective and antibacterial properties. The chemical composition of Centauruim erythraea essential oils (CEEO) was determined using GC/MS analysis. 39 volatile compounds were identified, belonging mainly to oxygenated monoterpenes, 51.63%, 44.10% and 53.69% at ...
Published on Apr 1, 2019in Food Chemistry 5.40
Mohamed Reda Kachmar , Andreia Oliveira20
Estimated H-index: 20
(University of Porto)
+ 6 AuthorsFederico Ferreres60
Estimated H-index: 60
(CSIC: Spanish National Research Council)
Abstract Centaurium erythraea Rafn is a food flavouring used in both food and beverage industries. Despite the existence of some works on this species, only few focus their attention on its common form of consumption (infusion). Thus, we intended to explore the chemical composition and the biological properties of infusions from C. erythraea aerial parts. Phenolic compounds were identified by HPLC–DAD–ESI/MS n , twenty-two flavonoid derivatives being reported for the first time. Concerning to th...
Published on Dec 1, 2018in Clinical Phytoscience
Vladimir Dlin (RSMU: Russian National Research Medical University), Dimitri Abramov-Sommariva3
Estimated H-index: 3
+ 10 AuthorsAlbina A. Vyalkova
Background A herbal medicinal product (HMP) with centaury, lovage, and rosemary as active ingredients (brand name: Canephron® N) has been widely used for treatment and prevention of urinary tract infections (UTIs) and other urinary system disorders. Non-clinical in vitro and in vivo data indicate its diuretic, spasmolytic, anti-inflammatory, antioxidative and analgesic effects. The purpose of this non-interventional, prospective, multicenter study was to collect data on the use of the HMP in the...
Published on Sep 1, 2018in Physiology and Molecular Biology of Plants 1.54
Sarah Megateli1
Estimated H-index: 1
,
Mohamed Krea1
Estimated H-index: 1
Electromagnetic induction heating (EMIH) assisted extraction of phenolic compounds from Rosmarinus officinalis L, and the antioxidant and antimicrobial activities of the plant extract were examined in this study. The extraction yield acquired with this process was found to be 25.1 ± 2%, with maximum amounts of phenolic compounds: 127.87 ± 2.1 mg Gallic acid equivalents per g dry weight and total flavonoids contents 14.48 ± 1.5 mg quercetin equivalents per g dry weight, under optimum extraction c...
Published on Sep 1, 2018in International Journal of Tropical Insect Science 0.85
Karima Hannour1
Estimated H-index: 1
,
Ahmed Boughdad1
Estimated H-index: 1
+ 1 AuthorsAziz Bouchelta1
Estimated H-index: 1
Control methods used to limit field losses caused by Bruchus rufimanus Boheman, 1833 consist of synthetic insecticides that pose health risks to farmers, consumers and the environment. In an attempt to find safer alternatives, we screened essential oils from the leaves of Rosmarinus officinalis collected in the Middle Atlas and Loukkos regions of Morocco in the laboratory as natural fumigants against B. rufimanus. These essential oils were extracted by steam distillation using a Clevenger distil...
Published on Jun 1, 2018in Basic & Clinical Pharmacology & Toxicology 2.45
Geir Bjørklund18
Estimated H-index: 18
,
Maryam Dadar15
Estimated H-index: 15
(Razi Vaccine and Serum Research Institute)
+ 4 AuthorsRoman Lysiuk3
Estimated H-index: 3
(Danylo Halytsky Lviv National Medical University)