Multiplexed aberration measurement for deep tissue imaging in vivo

Volume: 11, Issue: 10, Pages: 1037 - 1040
Published: Oct 1, 2014
Abstract
We describe an adaptive optics method that modulates the intensity or phase of light rays at multiple pupil segments in parallel to determine the sample-induced aberration. Applicable to fluorescent protein-labeled structures of arbitrary complexity, it allowed us to obtain diffraction-limited resolution in various samples in vivo. For the strongly scattering mouse brain, a single aberration correction improved structural and functional imaging...
Paper Details
Title
Multiplexed aberration measurement for deep tissue imaging in vivo
Published Date
Oct 1, 2014
Volume
11
Issue
10
Pages
1037 - 1040
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