Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling
Abstract
Chronic inflammation constitutes an important link between obesity and its pathophysiological sequelae. In contrast to the belief that inflammatory signals exert a fundamentally negative impact on metabolism, we show that proinflammatory signaling in the adipocyte is in fact required for proper adipose tissue remodeling and expansion. Three mouse models with an adipose tissue-specific reduction in proinflammatory potential were generated that...
Paper Details
Title
Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling
Published Date
Jul 1, 2014
Journal
Volume
20
Issue
1
Pages
103 - 118
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