Perturbation of Rat Heart Plasma Membrane Fluidity Due to Metabolites of Permethrin Insecticide
Abstract
Due to increased global use, acute and chronic exposures to pyrethroid insecticides in humans are of clinical concern. Pyrethroids have a primary mode of action that involves interference with the sodium and calcium channels in excitable cells, which may include cardiac myocytes. Here, we investigated the possible cardiac toxicity of permethrin metabolites (METP), 3-phenoxy-benzyl alcohol (3PBA), 3-phenoxy-benzaldehyde (3PBALD), and...
Paper Details
Title
Perturbation of Rat Heart Plasma Membrane Fluidity Due to Metabolites of Permethrin Insecticide
Published Date
May 20, 2011
Journal
Volume
11
Issue
3
Pages
226 - 234
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