10-Hydroxy-2-decenoic acid from Royal jelly: A potential medicine for RA
Abstract
Rheumatoid arthritis synovial fibroblasts (RASFs) are known to produce matrix metalloproteinases (MMPs) and cause joint destruction. The purpose of this study is to develop a potential medicine for rheumatoid arthritis (RA).To this end, first, the MMPs inhibition factor was purified from an alkali-solubilized fraction of RJ (Apis mellifera) by C18 reverse-phase column chromatography and identified as 10-hydroxy-2-decenoic acid (10H2DA) by LTQ XL...
Paper Details
Title
10-Hydroxy-2-decenoic acid from Royal jelly: A potential medicine for RA
Published Date
Mar 1, 2010
Journal
Volume
128
Issue
2
Pages
314 - 321
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