Disseminated disease severity as a measure of virulence of Mycobacterium tuberculosis in the guinea pig model

Volume: 88, Issue: 4, Pages: 295 - 306
Published: Jul 1, 2008
Abstract
Virulence is the measure of pathogenicity of a microorganism as determined by its ability to invade host tissues and to produce severe disease. In the low-dose aerosol guinea pig model the virulence of multiple strains of Mycobacterium tuberculosis was determined by measuring time of survival, bacterial loads in target organs, and the severity of pulmonary and extra-pulmonary lesions. Erdman K01, CSU93/CDC1551 and HN878 had shorter survival...
Paper Details
Title
Disseminated disease severity as a measure of virulence of Mycobacterium tuberculosis in the guinea pig model
Published Date
Jul 1, 2008
Volume
88
Issue
4
Pages
295 - 306
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