At the tipping point for epigenetic therapies in cancer
Abstract
The field of epigenetics has exploded in the last two decades, with incredible advances in recent years driven by high-throughput sequencing studies. Cancer cells frequently exhibit marked changes in DNA methylation and histone modification during tumorigenesis and tumor progression. These changes in the cancer epigenome are thought to be important in initiating and maintaining malignancy, and pharmaceutical approaches targeting...
Paper Details
Title
At the tipping point for epigenetic therapies in cancer
Published Date
Jan 2, 2014
Volume
124
Issue
1
Pages
14 - 16
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History