Adipose Tissue Foam Cells Are Present in Human Obesity

Adipose tissue macrophages (ATMs) are thought to engulf the remains of dead adipocytes in obesity, potentially resulting in increased intracellular neutral lipid content. Lipid-laden macrophages (foam cells [FCs]) have been described in atherosclerotic lesions and have been proposed to contribute to vascular pathophysiology, which is enhanced in obesity. The objective of this study was to determine whether a subclass of lipid-laden ATMs (adipose...