Physicochemical and biological comparison of polyene macrolide antibiotics fungichromin, lagosin and cogomycin.
Abstract
The three polyene macrolide antibiotics, fungichromin, lagosin, and cogomycin, previously described as having some stereochemical differences at one or more centers, are shown by countercurrent distribution, high-performance liquid chromatography, carbon-13 nuclear magnetic resonance spectroscopy, circular dichroism, and biological studies to be identical in all respects, including stereochemical aspects. The differences observed earlier in...
Paper Details
Title
Physicochemical and biological comparison of polyene macrolide antibiotics fungichromin, lagosin and cogomycin.
Published Date
Jan 1, 1982
Journal
Volume
35
Issue
8
Pages
988 - 996
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