Effects of tributyltin and 17β-estradiol on immune and lysosomal systems of the Asian clam Corbicula fluminea (M.)

Freshwater clams Corbicula fluminea were experimentally exposed to a range of tributyltin (TBT) (50, 250 and 500 ng Sn/L) and 17β-estradiol (20, 200, 2000 ng/L) for 30 days. After 15 and 30 days, phagocytosis activity of haemocytes and lysosomal structural changes in the digestive cells were assayed. 17β-Estradiol exerted a higher inhibition on phagocytosis than tributyltin. This would suggest the existence of estrogen receptors, influencing the...