Volume-sensitive chloride current activated by hyposmotic swelling in antral gastric myocytes of the guinea-pig

Volume: 435, Issue: 1, Pages: 9 - 19
Published: Nov 17, 1997
Abstract
The characteristics of volume-sensitive chloride current (I Cl) induced by osmotic cell swelling were studied using the whole-cell patch-clamp technique and cell diameters of antral circular guinea-pig myocytes were simultaneously measured under isosmotic and hyposmotic conditions by using a video image analysis system. At –60 mV, osmotic cell swelling (200 mosmol/l) activated a sustained inward current. Instantaneous current/voltage (I-V)...
Paper Details
Title
Volume-sensitive chloride current activated by hyposmotic swelling in antral gastric myocytes of the guinea-pig
Published Date
Nov 17, 1997
Volume
435
Issue
1
Pages
9 - 19
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