Protective effects of ligustrazine on TNF-α-induced endothelial dysfunction
Abstract
To investigate the effects of Ligustrazine, a compound derived from chuanxiong, on tumor necrosis factor-α (TNF-α) stimulated endothelial cells. Human umbilical vein endothelial cells (HUVECs) were stimulated with TNF-α in vitro. Nitric oxide (NO) was measured as a standard of endothelial dysfunction. Two important indicators of autoimmunity, intracellular adhesion molecular-1 (ICAM-1) and heat shock protein 60 (HSP60), were selected to evaluate...
Paper Details
Title
Protective effects of ligustrazine on TNF-α-induced endothelial dysfunction
Published Date
Jan 15, 2012
Volume
674
Issue
2
Pages
365 - 369
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