Cefuroxime Pharmacokinetics in Continuous and Intermittent Peritoneal Dialysis
Abstract
Pharmacokinetics of cefuroxime was studied in patients on continuous ambulatory or intermittent peritoneal dialysis. A single intravenous bolus (15 mg/kg) of cefuroxime provided a mean serum concentration of 86 mg/litre 5 min, 40 mg/litre 1 h, 163 mg/litre 24 h after the injection. The peritoneal clearance of cefuroxime varied widely among different individuals, ranging from 1.45 to 6.17 ml/min with a mean of 3.59 ml/min during 4-hour exchanges,...
Paper Details
Title
Cefuroxime Pharmacokinetics in Continuous and Intermittent Peritoneal Dialysis
Published Date
Jan 1, 1985
Journal
Volume
41
Issue
2
Pages
161 - 165
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