Ovarian cancer screening with annual transvaginal sonography

BACKGROUND Ovarian cancer has the highest mortality rate of all gynecologic malignancies, and most women present with advanced‐stage disease. The current investigation was performed to determine the efficacy of annual transvaginal sonography (TVS) as a screening method for ovarian cancer. METHODS Annual TVS screening was performed on 25,327 women from 1987 to 2005. Asymptomatic women aged ≥50 years and women aged ≥25 years who had a family...