Mechanisms of induction of enzymes that protect against chemical carcinogenesis.
Abstract
A persuasive body of evidence indicates that substantial protection against chemical carcinogenesis can be achieved by induction of enzymes concerned with the metabolism of carcinogens. There are two classes of anticarcinogenic enzyme inducers: (a) monofunctional inducers (e.g., phenolic antioxidants, isothiocyanates, coumarins, thiocarbamates, cinnamates, 1,2-dithiol-3-thiones) that elevate Phase II enzymes (such as glutathione S-transferases,...
Paper Details
Title
Mechanisms of induction of enzymes that protect against chemical carcinogenesis.
Published Date
Jan 1, 1989
Volume
28
Pages
237 - 250
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